Early administration of umbilical cord blood cells following brief high tidal volume ventilation in preterm sheep: a cautionary tale

This is the authors' abstract. We don't add key points for this paper.

Umbilical cord blood (UCB) cells are a promising treatment for preterm brain injury. Access to allogeneic sources of UCB cells offer the potential for early administration to optimise their therapeutic capacities. As preterm infants often require ventilatory support, which can contribute to preterm brain injury, we investigated the efficacy of early UCB cell administration following ventilation to reduce white matter inflammation and injury.