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May 8, 2024Pathobiology

Expanding the Spectrum of Sarcoma with an Internal Tandem Duplication of BCOR: A Non-Pediatric Nasosinusal Case

Florian Piques Martin Penicaud Wassim Essamet Simon Cabello‐Aguilar Aude Trinquet Julie A. Vendrell Valérie Costes Jérôme Solassol

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Abstract

Undifferentiated small round-cell sarcomas with BCL6 corepressor (BCOR) alterations, such as an internal tandem duplication (ITD) within exon 15, are typically described as a pediatric group of Ewing-like small round-cell sarcomas.

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Piques et al. (2024) studied this question.

synapsesocial.com/papers/68e6b030b6db643587632222 https://doi.org/10.1159/000539239

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Central nervous system tumors with <i>BCOR</i> internal tandem duplications: a systematic review of clinical, radiological, and pathological features in 69 cases2025 · 2 citations
2Clinical and morphological features of central nervous system tumor with BCOR internal tandem duplicationOriginal Research · 2023
3BCOR overexpression in pediatric sarcomas- a morphologic continuum of mixed round and spindle cell tumors2024 · 1 citations
4Expanding the clinicopathologic and molecular spectrum of <i>BCOR</i>‐associated sarcomas in adultscase_series · 2019 · 59 citations
5Novel BCOR-MAML3 and ZC3H7B-BCOR Gene Fusions in Undifferentiated Small Blue Round Cell Sarcomasother · 2016 · 177 citations

More related papers

A Central Nervous System Tumor with BCOR Internal Tandem Duplication: Case Report of a Distinct Molecular Pediatric Entity2026
<i><scp>BCOR</scp>–<scp>CCNB</scp>3</i>‐positive soft tissue sarcoma with round‐cell and spindle‐cell histology: a series of four cases highlighting the pitfall of mimicking poorly differentiated synovial sarcoma2016
Ewing‐like sarcomas with <i>BCOR‐CCNB3</i> fusion transcript: A clinical, radiological and pathological retrospective study from the Société Française des Cancers de L'Enfant2014

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