Disseminated Fixed Drug Eruption: Unmasking a Rare Presentation of Furazolidone and Metronidazole Combination Therapy

Fixed drug eruption (FDE) is an uncommon cutaneous adverse reaction characterized by recurrent erythematous or violaceous plaques at fixed sites upon re-exposure to the culprit drug. We present a case of disseminated FDE in a 45-year-old male who developed widespread erythematous lesions involving multiple body sites following concurrent administration of furazolidone and metronidazole for gastrointestinal infection. Histopathological examination revealed typical features consistent with FDE. The patient was managed with cessation of the offending medications and supportive treatment, leading to resolution of the lesions without recurrence. This case underscores the importance of recognizing disseminated FDE as a potential adverse effect of commonly used medications, necessitating prompt identification and appropriate management strategies.