Utility of a multiplex pathogen detection system directly from respiratory specimens for treatment and diagnostic stewardship

Smriti Srivastava; Neha Sharad; Vandana Vijayeta Kiro; Aparna Ningombam; Sharad Shrivastava; Kamran Farooque; Purva Mathur

doi:10.1128/spectrum.03759-23

May 7, 2024Microbiology SpectrumOpen Access

Utility of a multiplex pathogen detection system directly from respiratory specimens for treatment and diagnostic stewardship

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Key Points

Syndrome-based panels achieve high diagnostic concordance with standard microbiological culture, reliably detecting pathogens directly from lower respiratory specimens.
Overall agreement reached 76.72% across all tested specimens, and positive agreement achieved 100% concordance with microbiological culture for fastidious bacteria.
Comparative assessment against microbiological culture confirms reliable identification of fastidious bacteria, supporting stewardship of antimicrobial resistance.

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Implication

Comparative evaluation demonstrates high diagnostic agreement for a multiplex panel in lower respiratory samples, highlighting utility for antimicrobial stewardship.

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Srivastava et al. (2024) studied this question.

synapsesocial.com/papers/68e6b291b6db643587633cb2 https://doi.org/10.1128/spectrum.03759-23

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Utility of a multiplex pathogen detection system directly from respiratory specimens for treatment and diagnostic stewardship

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Utility of a multiplex pathogen detection system directly from respiratory specimens for treatment and diagnostic stewardship

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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