Advancements in the Treatment of Recurrent Metastatic Colorectal Cancer

Radical resection is the main approach for achieving a cure in patients with recurrent liver metastasis of colorectal cancer. However, due to the limited liver volume and the tolerance of late-stage tumor patients, it is not possible to perform repeated resections infinitely. Therefore, the scope and timing of repetitive liver resection become critically important. In the opposing contradiction between the residual liver volume (FLR) and tumor burden, finding the most beneficial treatment plan for patients is the mission of precision medicine. The treatment of colorectal cancer liver metastasis emphasizes a Multidisciplinary Team (MDT) approach, aiming to achieve disease-free survival or prolong the patient’s survival.