Vitamin B12, or cobalamin, plays a crucial role in neurological and psychiatric health. This case report presents a 33 -yearold male with Bipolar Affective Disorder and severe mania, which included irritable mood, insomnia, and violent behavior. Despite initial treatments, he developed hypersomnolence and lethargy. Comprehensive testing revealed a significant vitamin B12 deficiency 100 picogramsmL. After intensive vitamin B12 therapy, the patients symptoms improved markedly. This report underscores the importance of recognizing and treating vitamin B12 deficiency in psychiatric conditions, highlighting a unique case where B12 deficiency was linked to both mania and hypersomnolence.
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Halder et al. (2024) studied this question.
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