A Comparative Study on Two Doses of Esmolol 0.5mg/Kg and 1.5mg/Kg to Attenuate the Hemo Dynamic Stress Response during Laryngoscopy and Endo Tracheal Intubation

This study investigates the optimal dose of esmolol to attenuate the hemodynamic response to laryngoscopy and endotracheal intubation.Conducted over six months at a tertiary healthcare center, 40 patients undergoing general surgical procedures were divided into two groups receiving either 0.5 mg/kg or 1.5 mg/kg of esmolol.Heart rate and blood pressure were monitored at baseline, during, and after intubation.The results showed that a 1.5 mg/kg dose of esmolol significantly reduced the increase in heart rate and blood pressure compared to the 0.5 mg/kg dose.The higher dose was more effective in minimizing the hemodynamic stress response, with no major side effects reported.