Observational analysis reveals epigenetic age acceleration in pediatric atopic dermatitis, highlighting dynamic DNA methylation biomarkers.
Atopic dermatitis (AD) is a chronic inflammatory skin disease resulting from the complex interplay of genetic and environmental factors, meriting exploration using temporally dynamic biomarkers. DNA methylation-based algorithms have been trained to accurately estimate biological age, and deviation of predicted age from true age (epigenetic age acceleration) has been implicated in several inflammatory diseases, including asthma.
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Jeremian et al. (2024) studied this question.
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