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May 3, 2024Frontiers in PharmacologyOpen Access

Genetic variation in UGT1A1 is not associated with altered liver biochemical parameters in healthy volunteers participating in bioequivalence trials

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EGEva González‐IglesiasHospital Universitario de La PrincesaDODolores OchoaHospital Universitario de La PrincesaMRManuel RománHospital Universitario de La Princesa

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Cite This Study

González‐Iglesias et al. (2024) studied this question.

synapsesocial.com/papers/68e6ba77b6db64358763b727https://doi.org/10.3389/fphar.2024.1389968
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Genetic, clinical, and biochemical profiling of Gilbert syndrome in a Nepali cohort: High prevalence of the UGT1A1 c.-3279T>G polymorphism and correlation with hematological parameters2026
  2. 2Beyond Gilbert syndrome: exploring the heterozygous UGT1A1 c.41_40dup variant as a potential modifier of bile composition associated with a cholangiopathic phenotype in adults with unexplained chronic cholestasis2026
  3. 3Results of UGT1A1 gene sequencing in individuals with the Gilbert syndrome phenotype2024 · 1 citations
  4. 4An Exploratory Study of the Association Between UGT1A1*28 Polymorphism and Polygenic Scores for General Intelligence in a High-Coverage Whole Genome Sequencing Cohort2026
  5. 5Studies of the UDP-glucuronosyltransferase enzymes family activity2026