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October 8, 2025Scholars Academic Journal of BiosciencesOpen Access

Evaluation of the Hypoglycemic and Antihyperglycemic Effect of Persea Americana (Lauraceae) Leaves in Wistar Strain Rats (Rattus norvegicus)

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Authors

AAABALE Louise Christelle AkouassoRJROBET Emilie JocelyneDRDJALEO Ouraga Rodolphe

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Overview

This study evaluates the hypoglycemic and antihyperglycemic effects of persea americana leaves in Wistar rats, indicating potential benefits for diabetes treatment.

Key Points

  • Persea americana leaves exhibited significant antihyperglycemic effects in Wistar rats, particularly at doses of 200 and 600 mg/kg BW.
  • The extract showed comparable blood glucose reduction to glibenclamide at 120 minutes after administration, indicating its potential utility.
  • Initial blood glucose levels significantly decreased from 1.72 g/l to 0.64 g/l with the 200 mg/kg dose, highlighting the extract's efficacy.
  • This study emphasizes the importance of exploring natural treatments for diabetes, as traditional medicine could provide valuable alternatives.

Cite This Study

Akouasso et al. (2025) studied this question.

synapsesocial.com/papers/68e6bc5f38ca8e474d549df8https://doi.org/10.36347/sajb.2025.v13i09.009
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of the Ameliorative Effects of Persea americana Seeds on the Biochemical and Hematological Parameters in Type 2 Diabetic Rats2024
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  3. 3Effects of Physalis peruviana L. (leaf crude extracts) on blood glucose and functional biomarkers in streptozotocin-nicotinamide-induced diabetic rats2024
  4. 4Effectiveness of avocado leaf extract (Persea americana Mill.) as antihypertensive2023 · 4 citations
  5. 5Comparative studies on the antidiabetic effects of extracts of Lepidium sativum L. seeds and Annona squamosa L. leaves on Streptozotocin-induced diabetic rats2026