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October 8, 2025NAR Genomics and BioinformaticsOpen Access

VIRUS-MVP: a framework for comprehensive surveillance of viral mutations and their functional impacts

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Authors

MAMuhammad Zohaib AnwarIGIvan S GillMIMadeline Iseminger

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Overview

Interactive tool enables real-time monitoring of viral mutations in SARS-CoV-2, mpox, and influenza, highlighting public health implications.

Key Points

  • VIRUS-MVP enhances understanding of viral evolution and public health impact with real-time tracking and annotations.
  • The platform links viral mutations to functional effects on viral infectivity and immune evasion, aiding response strategies.
  • Its open-source design allows users to import custom annotations, promoting flexible research for various pathogens.
  • Collaboration with public health and academic partners strengthens its applicability and relevance in epidemiological monitoring.

Cite This Study

Anwar et al. (2025) studied this question.

synapsesocial.com/papers/68e6bc5f38ca8e474d549e61https://doi.org/10.1093/nargab/lqaf132
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1MVP: a modular viromics pipeline to identify, filter, cluster, annotate, and bin viruses from metagenomes2024 · 6 citations
  2. 2CovMutEx: An Extensible Software Framework for ExploringSARS-CoV-2 Genome-Wide Mutation Probabilities2026
  3. 3PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space2026 · 1 citations
  4. 4Identification of Viral Variants from Functional Genomics Data2025
  5. 5A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike2022 · 20 citations