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May 2, 2024

Supplementary Figure 13 from Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling

Ruyi Zhang Shanshan Li Kelly Schippers Yunlong Li Boaz Eimers Marla Lavrijsen Ling Wang Guofei Cui Xin Chen Maikel P. Peppelenbosch Joyce H.G. Lebbink Ron Smits

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Abstract

Addition of an extra RGS/APC domain restores APC and β-catenin binding to selected RGS/APC domain variants, and (partially) restores β-catenin regulation

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Cite This Study

Zhang et al. (2024) studied this question.

synapsesocial.com/papers/68e6bea1b6db64358763e9cb https://doi.org/10.1158/0008-5472.25736000

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure 13 from Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling2024
2Supplementary Figure 11 from Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling2024
3Supplementary Figure 11 from Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling2024
4Supplementary Figure 10 from Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling2024
5Supplementary Figure 10 from Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling2024