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May 1, 2024HeliyonOpen Access

Dual blockage of PI3K-mTOR and FGFR induced autophagic cell death in cholangiocarcinoma cells

Narumon Mahaamnad Piman Pocasap Veerapol Kukongviriyapan Laddawan Senggunprai Auemduan Prawan Sarinya Kongpetch

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Abstract

To assess the impact of concurrent inhibition of the FGFR and PI3K/mTOR signaling pathways on oncogenic characteristics in cholangiocarcinoma (CCA) cells, including proliferation, autophagy, and cell death.

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Mahaamnad et al. (2024) studied this question.

synapsesocial.com/papers/68e6c1d6b6db643587641112 https://doi.org/10.1016/j.heliyon.2024.e31112

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