Toxicity Evaluation with Brine Shrimp Lethality Test and Phytochemical Analysis of Some Indonesian Plant Extracts As Potential Anti-Colon Cancer Agents

Garlic (Allium sativum), red ginger (Zingiber officinale), turmeric (Curcuma longa), tea (Camelliasinensis), tomato (Solanum lycopersicum), bitter melon (Momordica charantia), pearl grass(Hedyotis corymbosa (L.) Lamk.), soybean (Glycine max), grape (Vitis venifera) and Sambiloto(Andrographis paniculata) were studied for their anticancer potential in colon cancer. Using acombination of these plants as promising anticancer agents still requires further exploration fromthe cultivation and formulation. This research was aimed at the phytochemical analysis andevaluation of the anticancer potential of these plants in colon cancer. The Brine Shrimp Lethalitytoxicity test using Artemia salina Leach larvae was used to determine the LC50 value of the plantextracts. Two of the ten plants with the lowest LC50 values include turmeric and ginger, withcytotoxicity values of 15.995 ppm and 3.488 ppm, respectively.