Diagnosis of primary hyperparathyroidism (PHPT) is difficult during pregnancy owing to the non-specific nature of signs and symptoms. Pregnant women with a calcium level over 2.85 mmol/L (11.4 mg/dL) and prior pregnancy loss are at high risk of maternal complications and fetal loss. Around one-half of neonates born to mothers with untreated PHPT have hypocalcemia and tetany. Therefore, early diagnosis and management of PHPT is crucial to avoid complications.
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Gummalla et al. (2024) studied this question.
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