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May 1, 2024Research and Practice in Thrombosis and HaemostasisOpen Access

TMX1 negatively regulates coagulation and phosphatidylserine exposure

Junsong Zhou Mario C Rico Lubica Rauova Mortimer Poncz David W. Essex

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Abstract

Five secreted platelet protein disulfide isomerases (PDIs) and 1 transmembrane PDI regulate platelet function and thrombosis. Thioredoxin-related transmembrane protein 1 (TMX1) was the first member of the PDI family found to negatively regulate platelet aggregation and platelet accumulation

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Cite This Study

Zhou et al. (2024) studied this question.

synapsesocial.com/papers/68e6c4a9b6db6435876430cf https://doi.org/10.1016/j.rpth.2024.102472

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