ComparativeAnalysis of Post-Operative Analgesia and Adverse Effects with PENG Block

Background: Pericapsular nerve group (PENG) is a novel regional anesthesia technique targeting articular branches of femoral, obturator and accessory obturator nerves.It is gaining attention for its potential to provide effective analgesia for hip fractures.The present study was designed to conduct a comparative analysis of post-operative analgesia and adverse effects associated with the PENG block.Methods: The study involved 50 patients aged 18-60 years, undergoing elective surgeries.Patients were divided into two groups of PENG block: RF (50mcg of fentanyl added to 30ml of 0.5% ropivacaine) and RD (50mcg of dexmedetomidine added to 30ml of 0.5% ropivacaine).Patients were administered tablets Alprazolam and Pantoprazole the night before surgery, and sensory blocks were evaluated at regular intervals until rescue analgesia and complete regression were achieved. Results:The study discovered that the distribution of demographic factors, including age and gender, was comparable between the two groups.In Group RF, the male-to-female ratio was 16:9, while in Group RD, it was 20:5, with no statistically significant variation.Group RD had an ASA I/II grade of 18/7, while Group RF had an ASA grade distribution of 19/6.Group RD had sensory blockade onset faster (1.8±0.5 mins) than Group RF (2.4±1.0 mins).Fentanyl or dexmedetomidine added to ropivacaine enhanced postoperative analgesia, lengthened the duration of anesthesia, and improved the onset of sensory block.Conclusion: Dexmedetomidine and fentanyl improve surgery readiness by shortening block onset time, prolonging sensory block duration, and extending post-operative analgesia.They also improve block quality with good sedation, making 50 μg of dexmedetomidine safe for use with ropivacaine.