A-75 | Performance of a Novel Miniaturized Robotic System in Percutaneous Coronary Intervention: A Pre-clinical Ex VivoStudy

A novel miniaturized robot (m-robot) has been developed as a disposable, single-use endovascular robot, but its use in percutaneous coronary intervention (PCI) has not been adequately investigated. This pre-clinical study compared PCI performance metrics of the m-robot to an established robotic system and manual controls. The ex vivo model in this study consisted of an endovascular simulator (VIST G7, Mentice) into which interventional devices are inserted. Subsequent advancement, retraction, and torquing of devices are displayed on a bedside fluoroscopic monitor using the vasculature of a simulated patient. Ten consecutive and unique PCI cases performed with the m-robot (LIBERTY®, Microbot Medical) were compared to PCI performed manually and by an established robotic system (CorPath GRX, Corindus). In all cases, device delivery times (tip of guide catheter to target lesion) for guidewires, balloons, and stents were measured and compared between groups. In all cases, the m-robot successfully performed PCI without conversion to manual. No significant differences were observed between the m-robot and manual control group for delivery times of guidewires, balloons, or stents (Table). In contrast, the m-robot delivered guidewires, stents, and post-dilation balloons significantly faster than an established robot (Table). In this pre-clinical evaluation using a disposable miniaturized robot to perform PCI, the m-robot performed similarly to manual procedures, but delivered PCI devices more efficiently than an established robotic system. These results support future in vivo studies of the m-robot in PCI.