C-48 | Real World Comparative Outcomes of Left Main and Non-Left Main Percutaneous Coronary Intervention

There are limited data comparing 'real world' left main (LM) and non-left main (non-LM) percutaneous coronary intervention (PCI) outcomes. Herein we report comparative features and outcomes (peri-procedural and 30-day major adverse cardiovascular events or MACE) of 468 PCI patients (210 LM and 258 non-LM) between 2019-2023 from a single center within the Baylor Scott & White Health System, compiled in the XLCath Registry. Mean age 69.6±10.3 years, 32% women. Significantly greater proportion in the LM group had chronic lung disease (28.9% vs 9.6%) and kidney disease (31% vs 19.5%), prior myocardial infarction (39.4% vs 17.6%), left ventricular (LV) dysfunction or cardiomyopathy (34.3% vs 7.7%) and prior CABG (51% vs 16.3%) compared with non-LM (p<0.01 for all comparisons). Worsening angina was the most frequent indication. Mechanical circulatory support (MCS) was employed in 8 (38%) vs 1 (0.38%) patients. Multivessel PCI was performed in 72.9% in LM and 15.5% in non-LM groups (p<0.001). Technical success was 92.8% vs 98.8% in LM and non-LM groups, respectively (p<0.0008). Peri-procedural and 30-days MACE are shown in Figure 1. Although Left Main PCI shows more peri-procedural complications, it has no differences in 30-days MACE or adverse events.