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Stroke remains one of the significant adverse events associated with high mortality within first year of left ventricular assist device (LVAD) implantation. Limited studies have evaluated the rate of stroke post LVAD implantation Hypothesis:: We hypothesize that patients with hemorrhagic stroke (HS) have higher mortality compared with ischemic stroke (IS) in patients post LVAD implantation. Secondary data analysis was performed using National Inpatients Sample (NIS) from 2016-2018. LVAD patients (02HA0QZ), IS (I63.0-I63.9), HS (I60.0-I60.9 and I61.0-I61.9 using international classification of diseases – ICD 10 PCS codes.). Multivariable logistic regression model is used to identify risk factors for mortality. A total of 2116 patients underwent LVAD implantation. 21 patients had HS, 76 IS. Majority of patients were male, Caucasians with a mean age of 56.79 ± 13.18. In-hospital mortality rate was 28.6% in HS compared to 27.6% in IS (p <0.0001), Table 1. Patients with HS had a higher odds ratio (OR 5.33, 95% CI 1.96-14.49, p = 0.0011) for in-hospital mortality compared with those without stroke. Cardiac arrest had an odds ratio (OR 5.69, 95% CI 2.86-11.33, p < 0.0001) similar to HS. HS has more catastrophic outcomes than IS including higher mortality and length of stay. HS carries an odds ratio similar to cardiac arrest for in-hospital mortality. Strategies to reduce strokes, particularly hemorrhagic, are warranted but should not limit patient selection for LVAD placement
Dixit et al. (Wed,) studied this question.