OR6-10 | Demographic Trends in ST-Elevation Myocardial Infarction Incidence and Mortality in the United States

With medical development various cardiovascular disease have experienced drastic changes in management and incidence and ST-segment elevation myocardial infarction (STEMI) is no exception. We aimed to analyze demographic trends in STEMI hospitalizations in the United States using nationwide inpatient data from 2004 to 2020. We calculated annual hospitalization per population rates and assessed trend through regression analysis. A total of 3,426,898 eligible patients were analyzed. The overall incidence of STEMI steadily decreased from 98.7 in 2004 to 49 per 100,000 inpatient hospitalizations per population in 2020 (p-trend < 0.01), primarily among older individuals. STEMI incidence increased in small and medium-sized hospitals but decreased in large hospitals. Higher STEMI incidence and mortality were observed in the lower-income population. Rates of PCI increased, while CABG rates decreased. Mortality decreased for individuals over 85 (25% to 22%) and for those aged 65-84 (13% to 10.5%). In the 45-65 age group, mortality slightly rose from 4% to 5.5%. Patients aged 18-44 maintained a consistent mortality rate around 2.5-3%. 17 years nationwide data reveals a consistent decline in STEMI incidence, particularly among older individuals. These findings, alongside variations across hospital sizes, disparities in lower income populations, and shifts in treatment modalities, underscore dynamic trends in STEMI epidemiology and management, reflecting the impact of evolving medical practices.