#1703177 The Flip Flopping Thyroid Disease: A Case of Transformation of Hashimoto Thyroiditis to Graves Disease

Hashimoto Thyroiditis (HT) and Graves Disease (GD) have historically been considered separate disease processes but are now understood to lie along a spectrum of autoimmune thyroiditis. More recent research suggests that HT is mediated by a cellular immune response and GD by a humoral response. While 10-15% of GD cases have been known to transition to HT, the reverse is much rarer. Here we present the unusual case of a patient with HT who converted to GD and then had oscillating features of both hyper- and hypothyroidism.