#1698476 Title: Disproportionate Hyperprolactinemia in a Patient with ESRD and Functioning Pituitary Adenoma

Prolactin, an anterior pituitary hormone secreted by lactotrophs. Prolactinomas are most common pituitary adenomas and show a 10:1 female-to-male incidence ratio.Types include microadenomas (< 1cm), macroadenomas (1-4 cm), and giant adenomas ( >4 cm). Studies show correlation between adenoma size and hyperprolactinemia, with microadenomas (< 200 ng/mL), macroadenomas (200-1000 ng/mL), and giant adenomas ( >1000 ng/mL). Hyperprolactinemia is common in ESRD patients, with highest reported level up to 600 ng/ml.