#1707580 A Perplexing Case of Panhypopituitarism and Central Diabetes Insipidus Found to be due to Primary Central Nervous System Lymphoma

Primary Central Nervous System Lymphoma (PCNSL) is a rare but well-known form of extra nodal lymphoma which accounts for less than 3% of intracranial tumors. Ninety percent of PCNSL cases are diffuse large B cell lymphoma (DLBCL) and it involves various brain structures, most often located around the ventricles. CNS lymphoma presenting as a mass involving the hypothalamus is rare with data limited to very few case reports. The most common symptoms of hypothalamic lesions are diabetes insipidus (DI), hypernatremia and disorders of food intake, sleep, and behavior.