Assessment of the Cart-I Plus for Cuffless Blood Pressure Monitoring: A Comparative Study With Standard Abpm Across Diverse Patient Subgroups

Objective: This study aimed to assess the accuracy of the CART-I Plus device, a novel ring-type cuffless blood pressure (BP) measuring device, across various ages, genders, and medication statuses, in comparison with standard ambulatory blood pressure monitoring (ABPM). Design and method: Design and Method: Forty patients were enrolled in the study, with thirty-three completing it. They were asked to simultaneously wear the CART-I Plus device, which measures blood pressure using photoplethysmography, and a standard ABPM device for about 24 hours. To assess the accuracy of the CART-I Plus, we conducted subgroup analyses based on age, gender, and medication status, comparing these specific groups to see how well the device performed across different patient profiles. Results: The CART-I Plus demonstrated strong correlation with the ABPM across various patient subgroups divided by age, sex, and medication use. For individuals under 52, Pearson’s correlation coefficients ranged from 0.81 to 0.93. The correlation was similarly robust in participants aged 52 and over (ranging from 0.83 to 0.95), with the highest observed in nighttime diastolic readings (r=0.95). Gender-specific analyses revealed very high correlations in males (up to r=0.98 for nighttime systolic readings) and strong correlations in females, albeit slightly lower. Medication status also showed strong correlations, with those on treatment displaying coefficients from 0.83 to 0.94, and those without from 0.80 to 0.90. Conclusions: The CART-I Plus device displays a high degree of concordance with ABPM, suggesting its potential utility for reliable, cuffless BP monitoring across diverse patient populations. The significant correlations in all subgroups, especially in nighttime readings and among those not on medication, underscore its promise for continuous, non-invasive BP measurement in various clinical scenarios.