Assessment of Hemostatic Efficacy of Feracrylum in Endonasal Surgical Interventions: A Randomized Controlled Study

Background: Endoscopic nasal surgery, a minimally invasive technique, often requires nasal packing to manage bleeding and prevent complications.This study aimed to evaluate Feracrylum's coagulation, antimicrobial, and hygroscopic efficacy in mitigating the drawbacks of nasal packing.Methods: A randomised controlled study included participants undergoing endonasal surgeries.Group A received topical Feracrylum, while Group B served as the control.On pack removal day, patients were assessed for nasal pack soakage, dressing changes, pain, and the need for tranexamic acid.On postoperative day 7, nasal cavities were examined for crusting and signs of infection.Adhesions and nasal mucosa condition were assessed on postoperative day 14. Results:The age distribution of the total 40 participants was balanced across the two groups, with 29 (72.5%)patients falling into the second decade of life.In group A, 5 (25%) patients dressings were soaked, compared to 12 (60%) in group B (p=0.05).No dressing changes were needed in group A. Group A showed fewer bleeding and pain scores during pack removal compared to group B (p<0.001).There were significant differences in post-operative day 7 evaluation between the groups, whereas adhesions were less frequent in group A than in group B during post-operative day 14 revaluation.Conclusions: Topical feracrylum post-endonasal surgeries reduce postoperative hemorrhage, dressing soakage, and the need for other hemostatic agents.It also eases nasal pack removal and decreases repacking incidence.