Abstract 3030: Age-sex Differences In The Global Burden Of Stroke Attributable To Particulate Matter Air Pollution In G20 Countries From 1990-2019: A Benchmarking Analysis

Introduction: Stroke stands as the primary contributor to both fatalities and disability worldwide, accounting for 12.68% of deaths within G20 nations. Among the various modifiable risk factors for stroke, air pollution emerges as a prominent culprit, particularly due to the escalating levels of industrial and automotive emissions on a global scale. Method: Using Global Burden of Disease tool, we analyzed deaths, disability-adjusted life years (DALYs), and years lived with disability (YLDs), attributable to particulate matter pollution. This pollution encompasses ambient particulate matter and household air pollution arising from solid fuels. Our analysis was stratified by age, gender, year, and location across G20 Countries, spanning the period from 1990 to 2019. Result: From 1990 to 2019, the total number of deaths saw an average annual increase of 17% (95%UI: 1-36%), and DALYs rose by 11% (3-26%). China experienced the highest increase in deaths (353%), followed by India (349%) and Turkey (208%), while Estonia saw a decrease. In 2019, Saudi Arabia had the highest mortality rate at 31.3 per 100,000, with Bulgaria at 24.33. The 70-74 age group had the highest deaths from household air pollution (44,241), and the most deaths from ambient air pollution (132,188). The 65-69 age group saw the highest DALYs due to household (1,077,344) and ambient particulate matter pollution (3,083,347). In 2019, strokes linked to household air pollution were higher in females, while males were more impacted by ambient particulate matter pollution. Conclusion: This study underscores the pervasive threat posed by stroke on a global scale and emphasizes the significant role of air pollution, in exacerbating this crisis. The observed upward trend in stroke-related deaths and DALYs over the past three decades calls for immediate action in implementing pollution control measures and public health interventions to mitigate the growing burden of stroke.