Experimental evaluation demonstrates a synergistic nanoplatform for apical periodontitis, suggesting enhanced bacterial eradication and bone repair.
The main issues faced during the treatment of apical periodontitis are the management of bacterial infection and the facilitation of the repair of alveolar bone defects to shorten disease duration. Conventional root canal irrigants are limited in their efficacy and are associated with several side effects. This study introduces a synergistic therapy based on nitric oxide (NO) and antimicrobial photodynamic therapy (aPDT) for the treatment of apical periodontitis.
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Zeng et al. (2024) studied this question.
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