Chitosan (CTS) has been a popular option for scaffold fabrication because of its biocompatibility, biodegradability, antimicrobial and nonimmunogenic effects. However, it is of limited function, due to its low mechanical strength and its solubility in acidified media. These limitations could be overcome by its blending with PVA and incorporation with bioactive materials to improve its mechanical properties and tissue regeneration capability.
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Ali et al. (2024) studied this question.
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