Solvent Free Green Synthesis f 4-Substituted Thiocarbamido- Naphthols

Recently in this laboratory we developed new solvent free green synthetic methods for the synthesis of 4-phenylthiocarbamido-1-naphthol, 4-(p-chloro)phenylthiocarbamido-1-naphthol, 4-(o-methyl)phenylthiocarbamido-1-naphthol, 4-(p-methyl)phenylthiocarbamido-1-naphthol, and 4-(m-methyl)phenylthiocarbamido-1-naphthol by interacting 4-amino-1-naphthol with p-chlorophenylisothiocynate, p-tolylisothiocynate, o-tolylisothiocynate and m-tolylisothiocynate in presence of sweet lemon juice, lemon and orange juice respectively which are hither to unknown. Yet such attempts were not carried out by any researcher for 4-amino-1-naphthol. Previous researchers carried out such type of synthesis for different molecules in organic solvents as medium, which are hazardous and make pollution of environment. Newly synthesized substituted thiocarbamidonapthols was characterized by elemental analysis, chemical characteristics and spectral studies.