A one‐pot protocol for the synthesis of amides has been developed by employing acetonitrile as nitrogen source and solvent. The reaction undergoes ring‐opening of cyclopropyl carbinols and in situ formation of homoallylic carbocation, which reacts with acetonitrile to give desired products. The substrate of this reaction is widely applicable and the desired products are obtained in moderate to good yields.
No takes yet. Share an insight, caveat, or question.
Zhou et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: