Research Progress of traditional Chinese Medicine monomers in Vascular Protection

Cardiovascular disease is seriously harmful to human health, and its mortality and disability rate are increasing, which brings heavy economic pressure to ordinary families.The pathogenesis of most cardiovascular diseases is derived from atherosclerosis, which can cause coronary arteriosclerosis and then cause myocardial infarction.At present, the commonly used anti-atherosclerotic drugs are lipid-lowering drugs, antioxidant drugs and anti-platelet aggregation drugs.Although effective, long-term use of the above drugs will cause adverse reactions such as liver function damage and gastrointestinal bleeding.Some studies have shown that traditional Chinese medicine monomer has a significant effect on atherosclerosis.Because of its many targets, few side effects and economical advantages, it has become a research hotspot in the treatment of cardiovascular diseases.This paper briefly reviews the research progress of anti-AS endothelial cell injury induced by traditional Chinese medicine monomer in four aspects: cell injury caused by antioxidant stress, regulation of vasoactive substances produced by endothelial cells, regulation of adhesion molecules on endothelial cell surface and regulation of lipids.