Multicomponent Tandem Cyclization/Aromatization Reaction: Access to 2‐Substituted Naphthothiazoles and Benzothiazoles

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A straightforward, metal‐free multicomponent tandem cyclization/aromatization approach for the synthesis of naphthothiazoles and benzothiazoles is described. This method employs α ‐tetralones and cyclohexenones as the starting materials, styrene derivatives as a one‐carbon synthon, an ammonium salt as the N source, elemental sulfur as the S source and an oxidant. This approach offers a broad substrate scope, including α ‐tetralones and cyclohexenones adorned with different functional groups, resulting in moderate to high yields of the desired products.