2-Quinolone (1,2-dihydroquinoline) and 1-aza coumarin derivatives are quinoline class pharmacophore structures known for their versatile bioactive and stable photophysical properties. In the present study, N-amino (2) and N-acetamido (3) derivatives of 2-quinolone-based 1-aza Coumarin-3-carboxylic acid were synthesized. Structure characterizations of the synthesized compounds were performed using 1H NMR, IR, 13C NMR spectral techniques. The synthesized compounds are thought to be precursor structures for the development of new bioactive agents because of their structural similarity. The photophysical sensitivities of compounds (2 and 3), which have the 1-Aza coumarin skeleton, in different solvents were examined by ultraviolet−visible (UV−Vis) absorption spectroscopy and fluorescence spectroscopy methods. In addition, the compounds synthesized in this study could serve as fluorophores, fluorescently active and bioactive new Schiff base sensors in different fluorescence studies.
No takes yet. Share an insight, caveat, or question.
Tahir Savran (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: