O-Acylhydroxylamine has been widely employed as an electrophilic amination reagent in transition-metal-catalyzed C–N coupling reactions, but its use as an electrophilic oxygen source has not been disclosed. Here, we report a Pd-catalyzed 1,2-oxyarylation of alkenes with O-acylhydroxylamines as an oxidant and an oxygen source for the first time. With simple amide as the monodentate directing group, this method features a broad substrate scope, good functional group tolerance, and mild conditions.
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Wang et al. (2024) studied this question.
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