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April 22, 2024Journal of Aerosol Medicine and Pulmonary Drug Delivery

Optimal Inhalation Profile of Pressurized Metered Dry Powder Inhaler Using a Valved Holding Chamber: A Dynamic Analysis

Tetsuri Kondo Toshimori Tanigaki Makoto Hibino Shigeto Horiuchi Kazunari Maeda Shunichi Tobe Riko Kamada Shigehiro Watanabe

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Abstract

: The combined use of a pressurized metered-dose inhaler and valved holding chamber (pMDI+VHC) is recommended to improve efficiency and safety; however, aerosol release is likely to vary with the inhalation maneuver. This

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Kondo et al. (2024) studied this question.

synapsesocial.com/papers/68e6e2d3b6db64358765e199 https://doi.org/10.1089/jamp.2023.0019

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