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Observational study observes varied response to synthetic progestins across steroid receptor expression levels in atypical endometrial hyperplasia, suggesting biomarkers for therapy.
Conservative management of atypical endometrial hyperplasia (AEH) or endometrial cancer (EMCA) often relies on the treatment of synthetic progestins, which show varied success and response rates. We evaluate the correlation between steroid receptor expression and response to progestin therapy in patients with AEH and EMCA.
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Zaiem et al. (2024) studied this question.
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