0502 Impact of Excessive Daytime Sleepiness on Day-to-day Experience of Patients Suffering from Obstructive Sleep Apnea

Abstract Introduction Today, excessive daytime sleepiness (EDS) is considered as one of the most frequently occurring clinical manifestations in patients with obstructive sleep apnea (OSA). According to the National Sleep Foundation 2000 Omnibus Sleep in America Poll: `a sizable proportion of adults (43%) report that they are so sleepy during the day that it interferes with their daily activities a few days per month or more; and, one out of five (20%) experience this level of daytime sleepiness at least a few days per week or more'. Methods Inclusion criteria The articles identified, were screened by title and abstract, and selected for full text review if they met the following inclusion criteria. 1)OSA and EDS should be primary or secondary outcomes and not incidental findings. 2)Studies showing clinical manifestations of EDS in patients with OSA such as problems with vigilance, cognitive function, memory, concentration, and mood; deterioration in school and/or job performance and productivity, social relationships, and driving skills Exclusion criteria Those articles and or studies were excluded from our analysis that included: 1)Patients who did not undergo the polysomnography.2)Patients who had pure or mainly central sleep apneas, co-morbidities, terminal illness 2)Patients with other causes of fatigue or excessive daytime sleepiness 3)Patients from pediatrics Results Our search strategy yielded 770 citations. Irrelevant papers were excluded by title and abstract review, leaving 72 manuscripts that were identified from the comprehensive database search. We read the titles of these articles specifically identify papers that looked at EDS and its impact on day to day life of patients suffering from. This eventually yielded the selection of 5 number of articles from their respective databases. Conclusion All of the included studies point towards a growing evidence that there is a strong correlation between EDS and OSA and how EDS affects the course of disease. Some negative effects of OSA are reduced productivity, cognitive dysfunction, frequent awakenings, disrupted sleep, irritability, judgment error and increased accident rates. OSA related EDS is related to neurocognitive function. Therefore, patients often have difficulty in concentrating and paying attention for long periods of time. Fine-motor coordination also gets affected. Support (if any)