0239 The Relationship Between Asthma and Sleep in Adolescents from the Future of Families and Child Wellbeing Study

Introduction Asthma has been linked to adverse sleep outcomes in adolescents but few studies have evaluated whether there are differences in the sleep health of adolescents with asthma from various racial/ethnic backgrounds. We aimed to test the association of asthma with sleep in a large, diverse, national sample of adolescents and to examine potential associations between race/ethnicity and sleep in those with asthma. Methods Data from 3307 adolescents were collected at the age-15 wave from the Future of Families and Child Wellbeing Study, a longitudinal birth cohort. Parent-reported asthma diagnosis and self-reported sleep measures, including bedtime, sleep duration, and number of nights/week with trouble falling asleep and staying asleep, were collected. Objective sleep measures, collected via actigraphy (n=784), included sleep onset, 24-hour sleep duration, sleep maintenance efficiency, and wake after sleep onset (WASO). Separate linear regression models were used to test the association between asthma and sleep outcomes in the entire sample, and to test the association between race/ethnicity and sleep outcomes in those with asthma (n=193-820). Models adjusted for age, sex, race/ethnicity, family structure, primary caregiver’s education, and household income to poverty ratio. Results Asthma diagnosis was significantly associated with more nights/week with trouble falling asleep in the entire sample (p<.001). Of those with asthma, 51.6% were African American, 25.1% were Hispanic/Latino, 11.8% were in the other category, and 11.5% were white. In those with asthma, race was significantly associated with multiple sleep outcomes. African American adolescents had an actigraphic sleep onset that was 1 hour earlier (p<.05) and reported sleeping 28.2 minutes less (p<.01) than white adolescents. Additionally, Hispanic/Latino adolescents had 9 more minutes of actigraphic WASO (p<.05) than white adolescents. Conclusion Overall we show that asthma is associated with more trouble falling asleep than those without asthma. Among those with asthma, we found shorter self-reported sleep duration and, unexpectedly, earlier sleep onset among African Americans and more WASO among Hispanic/Latino adolescents compared to White adolescents. Further studies should continue to explore the relationship between asthma and sleep by examining differences in asthma-related exposures that may underlie these sleep disparities. Support (if any) R25-HL147668, R01HD073352, R01HD36916, R01HD39135, R01HD40421