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Basal cell hyperplasia is commonly observed in nasal polyp epithelium of eCRS.We found that normal human bronchial epithelial(NHBE)cells obtained basal cell characteristics when cultured with PneumaCult TM -Ex Plus medium.Most of the cells expressed basal cell surface markers CD49f, CD271, and basal cell nuclear marker p63.We named these NHBE cells with basal cell characteristics, cultured Basal-like cells(cBC) , and NHBE cells cultured with BEGM TM , cultured Epithelial cells(cEC) .RNA sequencing revealed that cBC showed higher gene expression of thymic stromal lymphopoietin(TSLP) ,
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Nakamaru et al. (2024) studied this question.
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