International Session 15 Head and Neck-Clinical 2

In recent years, there has been a notable global increase in syphilis cases.This report presents a case of otosyphilis/ neurosyphilis.A 43-year-old male patient was referred to our clinic following the identification of bilateral moderate sensorineural hearing loss, which showed no improvement after initial treatment.Cochlear hearing loss was diagnosed, based on DPOAE and SISI test results.Although autoimmune diseases were initially suspected, tests including ANCA were negative for all antibodies.Despite undergoing prednisolone infusion therapy, the patient's hearing showed no improvement.A notable pharyngeal lesion led to positive syphilis serology results, confirming otosyphilis.Concurrently, meningitis was detected in cerebrospinal fluid tests, leading to a diagnosis of neurosyphilis.The treatment regimen included a two-week PCG infusion followed by a three-month oral Amoxicillin.This case reviews the pathology of hearing loss, including MRI and various auditory tests.Understanding the disease's characteristics and keeping it in the differential diagnosis is important for early diagnosis and critical for public health by preventing further spread.