Biocompatibility and coating potential of functionalized calciumphosphate nanoparticles on CI electrodes

Introduction Nanoparticles can serve as carrier substances for drugs, proteins and even nucleic acids. They penetrate the membrane of a target cell so that their conjugates can create intracellular effects. Also DNA, coding for a growth factor or anti-inflammatory factors,, can be transfected using the nanoparticles without any further reagents. However, there has been little research to date on whether this approach could play a role in the modeling of cochlear implant electrodes.