Case presentation of a patient with severe nasal polyposis: Use of primary biologic therapy without prior nasal sinus surgery

Introduction Biologic therapies represent new, highly effective treatment options for severe uncontrolled chronic rhinosinusitis with nasal polyposis (CRSwNP). In accordance with international and national recommendations and the eligibility criteria of biologics in the indication CRSwNP, biologic therapies are typically performed in patients who have previously undergone nasal sinus surgery and still have no control of the disease. In the case presentation, a patient with severe nasal polyposis will be presented with a primary biologic therapy.