Metabolic and transcriptomic profiling between eosinophilic and non-eosinophilic chronic rhinosinusitis: Understanding subtype-specific metabolomic differences

Intro Chronic Rhinosinusitis (CRS) comprises diverse inflammatory disorders, including eosinophilic (eCRS) and non-eosinophilic (neCRS) subtypes, each presenting unique immunological features. Understanding their metabolic and transcriptomic differences is vital for precise therapeutic strategies.