Interim analysis of a pilot study on the feasibility of sentinel lymph node biopsy for squamous cell carcinoma of the nasal cavity and paranasal sinus – SentiNose Pilot

Introduction To date, there are no clear recommendations for the treatment of a clinically inconspicuous neck in squamous cell carcinoma of the nose and paranasal sinuses. Prophylactic neck dissection or neck irradiation appears too aggressive given the relatively low occult metastasis rates. However, because the development of neck lymph node metastases is significantly associated with worse overall survival, patients at relevant risk for this need to be identified.