Prolonged bilateral periorbital edema as a manifestation of acute infectious mononucleosis

Introduction Infectious mononucleosis (IM) is an acute viral infection caused by the Epstein-Barr virus (EBV) and usually occurs with acute tonsillitis, fever, swollen and tender cervical lymph nodes, enlargement of liver and spleen. In our case a 33-year-old man was admitted to our emergency room due to progressive bilateral periorbital edema with an initially suspected allergic reaction. In addition, the patient was suffering from sore throat and was feeling generally unwell for several days though taking NSAR.