Introduction The diagnosis of CUP as metastasis of an unknown malignant primary tumor is always a diagnostic challenge. In addition to clinical and radiological diagnostics, a comprehensive histological examination is an integral part of the search for the primary tumor. Nevertheless, it is only possible to find a primary tumor in 40-60% of the cases. In this study, we report on the success rates of the diagnostic steps and the therapeutic outcome.
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Hammel et al. (2024) studied this question.
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