Examination of long-term development of therapy nonresponders and analysis of stimulation parameters and therapy usage duration in comparison to therapy responders in hypoglossal nerve stimulation

Introduction Hypoglossal nerve stimulation (HNS) effectively treats obstructive sleep apnea (OSA), but nonresponders (NR) occur at 28-34% (1). NR have not been well characterized so far. The aim of this study was to identify significant differences between therapy responders (R) to find potential predictors for a good therapy outcome.