⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

April 17, 2024PharmaceuticalsOpen Access

FRET Assays for the Identification of C. albicans HSP90-Sba1 and Human HSP90α-p23 Binding Inhibitors

Philip Kohlmann Sergey N. Krylov Pascal Marchand Joachim Jose

View Full Paper

Ask AI

Bookmark

Share

Abstract

Heat shock protein 90 (HSP90) is a critical target for anticancer and anti-fungal-infection therapies due to its central role as a molecular chaperone involved in protein folding and activation. In this study, we developed

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Kohlmann et al. (2024) studied this question.

synapsesocial.com/papers/68e6ebd7b6db643587666c7c https://doi.org/10.3390/ph17040516

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Improvement of Inhibitor Identification for Heat Shock Protein 90α by Utilizing a Red-Shifted Fluorescence Polarization ProbeOriginal Research · 2012 · 1 citations
2Hsp90 <i>β</i> ‐Selective Inhibitors: Probing the Solvent‐Accessible Frontier2025
3Structure-based discovery of small molecule inhibitors of FKBP51-Hsp90 protein-protein interaction2024 · 7 citations
4Insight into the Structural and Dynamic Properties of Novel HSP90 Inhibitors through DFT Calculations and Molecular Dynamics Simulations2024
5Discovery and development of inhibitors of heat shock factor 1 by a fluorescence polarization assay2025