This paper introduces a novel blood sample analysis method utilizing a bio-photonic sensor based on a dual defect layer photonic crystal within a one-dimensional topological structure. This structure is constructed with alternating silicon dioxide (SiO2) and zinc oxide (ZnO) layers and evaluated with a transfer matrix approach. Integrating defect layers in the photonic crystal structure facilitates the creation of localized resonant modes, enabling the detection of specific components. Analyzing the transmission spectrum with incident light that is enabled by photonic crystals with defect layers can be used in biosensing applications. In this paper, the one-dimensional photonic crystals with dual defect layer structure are explored for the analysis of blood samples. The dual defect layer structure increases the sensor's capability to detect and measure specific biomarkers in terms of sensitivity, selectivity, and detection limits. This innovation holds promise for continuous health monitoring, diagnostics, illness detection, and label-free, real-time blood sample monitoring. The combination of photonic crystal structures and the transfer matrix approach provides an adaptable framework for developing and optimizing biosensors with potential applications in healthcare and beyond.
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Sampath et al. (2024) studied this question.
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